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U.S. Congressman Don Beyer returns to Practical AI for another far-reaching conversation with Chris about many of the most important AI challenges facing America and the world. Blending political savvy and…
In this fully connected episode, Dan and Chris break down one of the biggest questions in AI today: do open vs. closed models still matter? From the rise of physical AI and edge devices to the shifting landscape of…
In this Fully-Connected episode, Dan and Chris start with Anthropic's Mythos frontier model, parsing what is publicly known about its cybersecurity capabilities and projecting its possible implications from "We've been…
Autonomous driving is not just a big tech or closed-source game, it's becoming accessible through open innovation and real-world deployment. Dan and Chris sit down with Harald Schäfer, CTO at Comma AI, to explore how…
In this fully connected episode, Dan and Chris break down the Anthropic Claude Code leak, what went wrong and what it reveals about agentic systems, AI architecture, and AI safety. They also explore how the open source…
AI is rapidly transforming how software is built, shifting economic incentives from open source code and collaboration toward on-demand, personalized development through agentic coding a.k.a. vibe coding. In this…
What does “AI at the edge” really mean in 2026, and why does it matter now more than ever before? In this episode, we’re joined by Brandon Shibley, Edge AI Solutions Engineering Lead at Qualcomm’s Edge Impulse, to…
What happens when an AI hater starts building with AI agents? In this episode, we talk with software engineer Steve Klabnik, known for his work on the Rust programming language, about his journey from criticizing AI to…
AI is reshaping global power, from chip manufacturing and computing power to AI governance and US-China relations. In this episode, Ben Buchanan, Assistant Professor at The Johns Hopkins University and former White…
As AI accelerates innovation and adoption, leaders are facing rising cognitive load, shifting systems, and new emotional realities inside their organizations. In this episode, Deloitte’s Chief Innovation Officer…
AI is moving fast from research to real-world deployment, and when things go wrong, the consequences are no longer hypothetical. In this episode, Sean McGregor, co-founder of the AI Verification & Evaluation Research…
AI agents are moving from demos to real workplaces, but what actually happens when they run a company? In this episode, journalist Evan Ratliff, host of Shell Game, joins Chris to discuss his immersive journalism…
As AI increasingly shapes geopolitics, elections, and civic life, its impact on democracy is becoming impossible to ignore. In this episode, Daniel and Chris are joined by security expert Bruce Schneier to explore how…
As generative AI moves into production, traditional guardrails and input/output filters can prove too slow, too expensive, and/or too limited. In this episode, Alizishaan Khatri of Wrynx joins Daniel and Chris to…
In this start-of-year FC episode, Chris and Daniel break down what really mattered in AI in 2025, and what to expect in 2026. They explore the rise of AI agents, the practical reality of multimodal AI, and how…
As AI reshapes the workplace, employees and leaders face questions about meaningful work, automation, and human impact. In this episode, Jason Beutler, CEO of RoboSource, shares how companies can rethink workflows…
Chris and Daniel talk with returning guest, Ramin Mohammadi, about how those seeking to get into AI Engineer/ Data Science jobs are expected to come in a mid level engineers (not entry level). They explore this growing…
Chris and Daniel unpack how AI-driven document processing has rapidly evolved well beyond traditional OCR with many technical advances that fly under the radar. They explore the progression from document structure…
This episode is a special crossover between the Practical AI podcast and The Changelog podcast. Chris was recently invited by longtime friends Jerod Santo and Adam Stacoviak, cohosts of The Changelog, to join them on…
Fireflies CEO, Krish Ramineni shares how the company is transforming AI-powered note-taking into a deeper layer of knowledge automation. He breaks down the technology behind real-time functionality like Live Assist…
Waymo’s VP of Research, Drago Anguelov, joins Practical AI to explore how advances in autonomy, vision models, and large-scale testing are shaping the future of driverless technology. The conversation dives into the…
Dan and Chris unpack whether today’s surge in AI deployment across enterprise workflows, manufacturing, healthcare, and scientific research signals a lasting transformation or an overhyped bubble. Drawing parallels to…
Dan and Chris sit down (again) with Jared Zoneraich, co-founder and CEO of PromptLayer, to discuss how prompt engineering has evolved into context engineering (and while loops with tool calls). Jared shares insights on…
In this fully connected episode, Daniel and Chris explore the emerging concept of tiny recursive networks introduced by Samsung AI, contrasting them with large transformer based models. They explore how these small…
As AI systems move from simple chatbots to complex agentic workflows, new security risks emerge. In this episode, Donato Capitella unpacks how increasingly complicated architectures are making agents fragile and…
Daniel sits down with Chelsea Linder, VP of Innovation and Entrepreneurship at TechPoint, to explore the what AI innovation and impact look like on the ground. They discuss Chelsea's journey from the VC world into…
Longtime friend of the show Rajiv Shah returns to unpack lessons from a year of building retrieval-augmented generation (RAG) pipelines and reasoning models integrations. We dive into why so many AI pilots stumble, why…
In this episode, Daniel and Chris are joined by Chris Aquino, software engineer at Thunderbird to hear the story of how they developed a privacy-preserving AI executive assistant. They discuss various design decisions…
In this Fully Connected episode, we dig into the recent MIT report revealing that 95% of AI pilots fail before reaching production and explore what it actually takes to succeed with AI solutions. We dive into the…
Daniel and Chris sit with Citadel AI’s Rick Kobayashi and Kenny Song and unpack AI safety and security challenges in the generative AI era. They compare Japan’s approach to AI adoption with the US’s, and explore the…
Dan and Chris break down Winning the Race: America's AI Action Plan, issued by the White House in July 2025. Structured as three "pillars" — Accelerate AI Innovation, Build American AI Infrastructure, and Lead in…
Allegra Guinan of Lumiera helps leaders turn uncertainty about AI into confident, strategic leadership. In this conversation, she brings some actionable insights for navigating the hype and complexity of AI. The…
Dan sits down with guests Mark Daniel Ward and Katie Sanders from The Data Mine at Purdue University to explore how higher education is evolving to meet the demands of the AI-driven workforce. They share how their…
We unpack how AI is reshaping hiring decisions, shifting job roles, and creating new expectations for professionals — from engineers to marketers. They explore the rise of AI-assisted teams, the growing compensation…
In this episode, Chris sits down with Igor Nikitin, CEO and co-founder of Nice Technologies, to explore how AI and modern engineering practices are transforming the actuarial field and setting the stage for the future…
In this episode of Practical AI, Chris and Daniel explore the fascinating world of agentic AI for drone and robotic swarms, which is Chris's passion and professional focus. They unpack how autonomous vehicles (UxV)…
In the first episode of an "AI in the shadows" theme, Chris and Daniel explore the increasing concerning world of agentic misalignment. Starting out with a reminder about hallucinations and reasoning models, they break…
In this episode, we sit down with Joey Conway to explore NVIDIA's open source AI, from the reasoning-focused Nemotron models built on top of Llama, to the blazing-fast Parakeet speech model. We chat about what makes…
Can AI-driven autonomy reduce harm, or does it risk dehumanizing decision-making? In this “AI Hot Takes & Debates” series episode, Daniel and Chris dive deep into the ethical crossroads of AI, autonomy, and military…
It seems like we are bombarded by news about millions of dollars pouring into AI startups, which have crazy valuations. In this episode, Chris and Dan dive deep into the highs, lows, and hard choices behind funding an…
An recent article in Variety was titled: "Sylvester Stallone-Backed Largo.ai Teams With Brilliant Pictures for ‘World’s First Fully AI-Automated Film Company’". Obviously this caught our attention! We sit down with…
Chong Shen from Flower Labs joins us to discuss what it really takes to build production-ready federated learning systems that work across data silos. We talk about the Flower framework and it's architecture…
In this first of a two part series of episodes on federated learning, we dive into the evolving world of federated learning and distributed AI frameworks with Patrick Foley from Intel. We explore how frameworks like…
Loïc Houssier, Head of Engineering at Superhuman, joins us to discuss how AI and LLMs are reshaping the email experience. He highlights challenges related to the variability of user prompts and infrastructure…
In this episode, Daniel and Chris unpack the Model Context Protocol (MCP), a rising standard for enabling agentic AI interactions with external systems, APIs, and data sources. They explore how MCP supports…
In this episode, we explore the intersection of AI, machine learning, and healthcare through the lens of neuroimaging and epilepsy diagnosis. Dr. Gavin Winston shares insights from his work using MRI data and machine…
Vibe coding, agentic workflows, and AI-assisted pull requests? In this episode, Daniel and Chris chat with Robert Brennan and Graham Neubig of All Hands AI about how AI is transforming software development—from senior…
In this episode, Daniel sits down with Pavel Veller, EPAM’s Chief Technologist, to explore the practical challenges of orchestrating many AI agents and managing connections to disparate systems/tools. Pavel shares…
How do you enable AI acceleration (at both the hardware and software layers) that stays ahead of rapid industry shifts? In this episode, Dhananjay Singh from Groq dives into the evolving landscape of AI inference and…
Kyle Daigle, COO of GitHub, joins the hosts to discuss the evolving role of AI in software development, GitHub Copilot’s impact, and the challenges of AI-assisted coding. The conversation covers licensing concerns…